Separation of enantiomers by chiral chromatography/chiral HPLC.

By Chiral HPLC/Chiral chromatography a very large number of chiral separations have been performed
using the chiral columns CHIRAL-AGP (USP chiral column L41), CHIRAL-CBH and CHIRAL-HSA.The
separation of enantiomers using chiral chromatography/chiral HPLC is today the dominating separation
technique of chiral compounds.
The CHIRAL-AGP column has extremely broad applicability. As can be seen from the applications a very
large number of basic, acidic and nonprotolytic drugs and related compounds have been separated into
enantiomers. The columns resolve chiral compounds containing primary-, secondary- or tertiary amino
groups or quarternary ammonium groups, as well as chiral compounds containing carboxylic acid functions
or weaker acidic groups as well as chiral nonprotolytes like alcohols, amides, sulphoxides, esters etc.

ChromTech's homepage is the most comprehensive Application Guide to chiral chromatography available
on the internet, containing hundreds of chiral separations of enantiomers on our chiral columns CHIRAL-AGP,
CHIRAL-CBH and CHIRAL-HSA.

Chiral Applications
Free Substance Screening
References
LC-MS columns
Products
Additional resources
Newsletters
Instruction Manuals
Application Literature
Additional products
Drug-protein binding
On-line extraction bioanalysis
Solid phase off-line extraction
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ChromTech Ltd, No. 2 The Courtyard, Greenfield Road, Congleton, Cheshire, CW12 4TR, U.K.
Phone: +44 (0)1260 270 153, Fax: +44 (0)1260 274 394, Email: sales@chromtech.co.uk